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Of such Atgs, Beclin one, the mammalian ortholog of yeast Atg6, interacts with class III PI3K (also named Vps34) and so plays a very important function inside the initiation of autophagosome development through autophagy7. Beclin 1 is the first autophagy-relevant tumor suppressor gene reported Up to now, and it's been shown to promote autophagy and

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